Li Xiaohui, Zhang Ziyang, Qin Shenying, Wang Tao, Liu Fangfei, Qiu Min, Su Yikai
Department of Electronic Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
Appl Opt. 2009 Sep 1;48(25):F90-4. doi: 10.1364/AO.48.000F90.
We propose an ultracompact parallel label-free biosensor based on concentric silicon-on-insulator microring resonators. Our numerical studies show that the proposed biosensor offers higher sensitivity and a larger detection area than conventional single-ring-based sensors. We analyze the detection sensitivity of the DNA hybridization by immobilizing the probe on top of the double concentric ring resonators and in the ring-ring air gap. For a concentric double-ring system with an area of 27.646 microm2, the bulk detection sensitivity is 683 nm RIU(-1). The sensitive uniformity of the system related to the optical field distribution is also studied.
我们提出了一种基于绝缘体上硅同心微环谐振器的超紧凑型并行无标记生物传感器。我们的数值研究表明，所提出的生物传感器比传统的基于单环的传感器具有更高的灵敏度和更大的检测面积。我们通过将探针固定在双同心环谐振器顶部和环-环气隙中来分析DNA杂交的检测灵敏度。对于面积为27.646平方微米的同心双环系统，整体检测灵敏度为683纳米/折射率单位（-1）。还研究了与光场分布相关的系统敏感均匀性。
