Osmers R, Völksen M, Schauer A
Department of Gynaecology and Obstetrics, University of Goettingen, West Germany.
Lancet. 1990 Jun 30;335(8705):1569-71. doi: 10.1016/0140-6736(90)91387-p.
In 103 women with postmenopausal bleeding and 283 postmenopausal women without bleeding maximum endometrial thickness was measured by vaginosonography. All patients with postmenopausal bleeding and all women without atypical bleeding but with an endometrium thicker than 4 mm or with some other indication for further investigation underwent curettage. The curettings were examined histologically. All histologically classified endometrial carcinomas were associated with an endometrial thickness of at least 4 mm. Endometrial cancer was found in 12.6% in the postmenopausal bleeding group (n = 103) and in 3.5% in the symptom-free group (n = 283). Vaginosonography is thus a good method of screening for uterine neoplasms in presymptomatic women--those with endometrial thickness of 4 mm or greater should undergo curettage and histological examination.
对103例绝经后出血的女性和283例绝经后未出血的女性进行经阴道超声检查，测量其最大子宫内膜厚度。所有绝经后出血的患者以及所有无非典型出血但子宫内膜厚度超过4mm或有其他进一步检查指征的女性均接受刮宫术。对刮宫组织进行组织学检查。所有组织学分类的子宫内膜癌均与子宫内膜厚度至少4mm相关。绝经后出血组（n = 103）中子宫内膜癌的检出率为12.6%，无症状组（n = 283）中为3.5%。因此，经阴道超声检查是对无症状女性子宫肿瘤进行筛查的一种好方法——子宫内膜厚度为4mm或更厚的女性应接受刮宫术和组织学检查。
