Reche-Sainz J A, García-Sáenz S, Toledano-Fernández N
Servicio de Oftalmología, Hospital de Madrid Norte-Sanchinarro, Madrid, España.
Arch Soc Esp Oftalmol. 2009 Aug;84(8):399-401. doi: 10.4321/s0365-66912009000800006.
A 58 year-old man with a known diagnosis of a large cell lung carcinoma, developed a progressive diplopia. His examination revealed a double oculomotor nerve palsy with dilated and poorly reactive pupils. A cranial magnetic resonance showed an unique and solitary lesion in the midbrain, which presumably affected to both oculomotor nucleus and fasciculus. There were not found additional extrathoracic manifestations.
This case shows the possibility that a large cell lung carcinoma may cause a double oculomotor nerve palsy as the consequence of an isolated midbrain metastasis.