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中脑血肿所致孤立性动眼神经核综合征

Isolated nuclear oculomotor nerve syndrome due to mesencephalic hematoma.

作者信息

Işikay C T, Yücesan C, Yücemen N, Culcuoglu A, Mutluer N

机构信息

Ankara University Faculty of Medicine, Department of Neurology, Ankara, Turkey.

出版信息

Acta Neurol Belg. 2000 Dec;100(4):248-51.

PMID:11233682
Abstract

Unilateral third nerve palsy with bilateral superior rectus paresis and bilateral ptosis is a typical condition for nuclear oculomotor nerve syndrome. We report a case of nuclear oculomotor nerve syndrome due to midbrain hemorrhage, as a rare cause. A 73-year-old man presented with an abrupt onset of double vision and difficulty opening his eyes. He had uncontrolled hypertension in his history. Neurological examination revealed right oculomotor palsy with impairment of bilateral upward gaze and bilateral ptosis. MRI showed a mesencephalic area of increased T1 signal and decreased T2 signal consistent with a subacute hematoma. It is emphasized that isolated mesencephalic hemorrhage may be the cause of the nuclear oculomotor nerve syndrome without associated neurological signs.

摘要

单侧动眼神经麻痹伴双侧上直肌麻痹和双侧上睑下垂是核性动眼神经综合征的典型表现。我们报告一例因中脑出血导致的核性动眼神经综合征病例,这是一种罕见病因。一名73岁男性突然出现复视和睁眼困难。他有高血压病史且血压控制不佳。神经系统检查发现右眼动眼神经麻痹,伴有双侧向上凝视障碍和双侧上睑下垂。MRI显示中脑区域T1信号增强、T2信号减弱,符合亚急性血肿表现。需要强调的是,孤立性中脑出血可能是核性动眼神经综合征的病因,且无相关神经系统体征。

相似文献

1
Isolated nuclear oculomotor nerve syndrome due to mesencephalic hematoma.中脑血肿所致孤立性动眼神经核综合征
Acta Neurol Belg. 2000 Dec;100(4):248-51.
2
[Isolated oculomotor nerve palsy caused by mesencephalic hemorrhage].[中脑出血所致孤立性动眼神经麻痹]
Rinsho Shinkeigaku. 1994 Oct;34(10):1021-5.
3
[Nuclear oculomotor nerve syndrome and ocular tilt reaction caused by mesencephalic hematoma].[中脑血肿所致核性动眼神经综合征及眼倾斜反应]
Rev Neurol (Paris). 1991;147(10):676-9.
4
[Brainstem ptosis (midbrain ptosis) associated with mesencephalic hemorrhage].
Rinsho Shinkeigaku. 1990 Jul;30(7):793-5.
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[Bilateral ptosis and upper gaze palsy with pupil sparing caused by midbrain hemorrhage].[中脑出血导致双侧上睑下垂和上视麻痹伴瞳孔保留]
No To Shinkei. 2005 Oct;57(10):899-901.
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[A case of partial fascicular oculomotor paresis caused by midbrain infarction].[一例由中脑梗死引起的部分束性动眼神经麻痹病例]
No To Shinkei. 2003 Mar;55(3):265-8.
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[Isolated nuclear oculomotor nerve palsy due to mesencephalic infarction].[中脑梗死所致孤立性核性动眼神经麻痹]
Rinsho Shinkeigaku. 1991 Feb;31(2):197-201.
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[Nuclear oculomotor nerve syndrome due to mesencephalic infarction or hemorrhage. Five cases and a review of literature].[中脑梗死或出血所致核性动眼神经综合征。5例报告并文献复习]
Neurologia. 1994 Jun-Jul;9(6):224-32.
9
Photo essay. Isolated fascicular third nerve palsy.图片集。孤立性束状第三神经麻痹。
J Neuroophthalmol. 2010 Sep;30(3):263-5. doi: 10.1097/WNO.0b013e3181ebb996.
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Midbrain hemorrhage presenting as bilateral ptosis without hemiplegia: a case report.
Zhonghua Yi Xue Za Zhi (Taipei). 1995 Feb;55(2):185-8.

引用本文的文献

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Isolated and Transient Nuclear Midbrain Blepharoptosis in a Young and Healthy Adult.一名年轻健康成年人的孤立性短暂性核性中脑上睑下垂
Neuroophthalmology. 2019 Mar 22;44(2):111-113. doi: 10.1080/01658107.2019.1588336. eCollection 2020 Apr.
2
Oculomotor palsy as a single presenting sign of midbrain hemorrhage.动眼神经麻痹作为中脑出血的单一表现体征。
Taiwan J Ophthalmol. 2018 Apr-Jun;8(2):108-110. doi: 10.4103/tjo.tjo_110_17.
3
Atypical isolated nuclear oculomotor nerve syndrome: a diagnostic challenge.非典型孤立性动眼神经核综合征:一项诊断挑战。
BMJ Case Rep. 2015 Feb 18;2015:bcr2014207749. doi: 10.1136/bcr-2014-207749.
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Isolated third, fourth, and sixth cranial nerve palsies from presumed microvascular versus other causes: a prospective study.疑似微血管性与其他原因所致孤立性第三、四、六对颅神经麻痹:一项前瞻性研究。
Ophthalmology. 2013 Nov;120(11):2264-9. doi: 10.1016/j.ophtha.2013.04.009. Epub 2013 Jun 6.