Tanaka K, Kambe N, Fujita M, Ando Y, Takashima S, Yuasa I
Department of Dermatology, Tottori University School of Medicine, Yonago, Japan.
Acta Derm Venereol. 1990;70(3):267-8.
Incontinentia pigmenti in female identical twins is reported. The first baby showed the typical pigmentation of incontinentia pigmenti, while the second baby had hydrocephalus (colpocephaly) without pigmentation. They were identical, with a rate of 99.9% in 18 blood-type studies. Virus was not detected and cytogenetic studies proved normal. Both showed peripheral eosinophilia. The individual expressions of Incontinentia pigmenti in these identical twins were separated into cutaneous lesions and lesion of the central nervous system (intra-uterine hydrocephalus). Cutaneous lesions developed after birth. Twins with Incontinentia pigmenti are extremely rare and in this family showed different expressions of this disease in space and time.
报道了一对女性同卵双胞胎患色素失禁症的病例。第一个婴儿表现出典型的色素失禁症色素沉着，而第二个婴儿有脑积水（脑室扩张）但无色素沉着。她们是同卵双胞胎，在18项血型研究中基因相同率为99.9%。未检测到病毒，细胞遗传学研究证明正常。两人均表现为外周嗜酸性粒细胞增多。这对同卵双胞胎中色素失禁症的个体表现分为皮肤病变和中枢神经系统病变（宫内脑积水）。皮肤病变在出生后出现。患色素失禁症的双胞胎极为罕见，在这个家族中该疾病在空间和时间上表现出不同的症状。
