罗红霉素和红霉素治疗衣原体阴性的非淋菌性尿道炎

Roxithromycin and erythromycin in chlamydia-negative non-gonococcal urethritis.

作者信息

Worm A M

机构信息

Department of Dermato-Venereology, Bispebjerg Hospital, Copenhagen, Denmark.

出版信息

Acta Derm Venereol. 1990;70(3):269-71.

PMID:1972850

Abstract

The clinical efficacy and safety of roxithromycin 300 mg once a day was compared with that of erythromycin 500 mg twice a day in 87 men with chlamydia-negative non-gonococcal urethritis. In the roxithromycin group the clinical efficacy rate was 88% on day 8 and between 78% and 84% on day 21. In the erythromycin group the clinical efficacy rate was 98% on day 8 and 86% on day 21, a non-significant difference. Side effects were mainly gastrointestinal, occurring in about 15% of patients receiving each treatment.

摘要

在87例衣原体阴性的非淋菌性尿道炎男性患者中，比较了每天一次服用300毫克罗红霉素与每天两次服用500毫克红霉素的临床疗效和安全性。罗红霉素组在第8天的临床有效率为88%，在第21天为78%至84%。红霉素组在第8天的临床有效率为98%，在第21天为86%，差异无统计学意义。副作用主要为胃肠道反应，接受每种治疗的患者中约15%出现该反应。