Upadhyaya L, Tiwari A K, Agrawal A, Dubey G P
Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
Act Nerv Super (Praha). 1990 Mar;32(1):1-5.
In the recent past, several herbal drugs have proved their efficacy in decreasing anxiety and tension. Until recently, limited scientific study has been done to prove the clinical importance of these herbal drugs. Geriforte is an indigenous compound commonly advocated for arresting the aging process. This remedy has also been found beneficial in reducing anxiety and stress.-34 diagnosed cases of anxiety neurosis and 24 apparently normal individuals were selected for the present study. After 12 weeks of drug therapy a significant reduction in 5-HT levels was observed. Circulating MAO and GABA showed an increasing trend along with decreased glutamic acid levels after treatment, in the neurotic anxiety cases. Psychological complaints considerably decreased after 12 weeks of therapy. Since Geriforte regulates the altered circulating biogenic amines, this remedy can be advocated as an adjunctive therapy in the management of stress disorders.
最近，几种草药已证明在减轻焦虑和紧张方面具有疗效。直到最近，为证明这些草药的临床重要性所做的科学研究还很有限。杰力福是一种常用于延缓衰老过程的本土化合物。这种疗法在减轻焦虑和压力方面也被发现是有益的。本研究选取了34例诊断为焦虑神经症的病例和24例明显正常的个体。经过12周的药物治疗后，观察到5-羟色胺水平显著降低。在神经症性焦虑病例中，治疗后循环单胺氧化酶和γ-氨基丁酸呈上升趋势，同时谷氨酸水平下降。经过12周的治疗，心理不适症状明显减轻。由于杰力福可调节改变的循环生物胺，因此这种疗法可作为应激障碍管理中的辅助治疗方法。
