[系统性红斑狼疮与爱泼斯坦-巴尔病毒]
[Systemic lupus erythematosus and Epstein-Barr virus].
作者信息
Tazi I, Fehri S, Elghrari K, Ouazzani T, Benchemsi N
机构信息
Laboratoire d'Hématologie, CHU Ibn Rochd, Casablanca, Maroc.
出版信息
East Mediterr Health J. 2009 May-Jun;15(3):701-8.
We determined the prevalence of antibodies to Epstein-Barr virus (EBV) in 44 patients with systemic lupus erythematosus (SLE) and 44 healthy blood donors matched for sex and age as controls. Of the cases, 39 were women; mean age was 33 years. Four cases (9%) and 5 controls (11%) were positive for IgM anti-viral capsid antigen (VCA) (P = 0.9). All the cases were positive for IgG anti-VCA compared with 91% of the controls (P = 0.12). The mean immunity ratio for this antibody was 2.341 in cases and 1.873 in controls (P = 0.068). Forty (91%) cases were positive for IgG anti-EBNA1 (EB nuclear antigen1) compared with 42 (95%) controls (P = 0.6).
我们测定了44例系统性红斑狼疮（SLE）患者及44名年龄和性别相匹配的健康献血者作为对照中抗爱泼斯坦-巴尔病毒（EBV）抗体的流行情况。病例组中，39例为女性；平均年龄为33岁。4例（9%）病例和5名对照（11%）的IgM抗病毒衣壳抗原（VCA）呈阳性（P = 0.9）。与91%的对照相比，所有病例的IgG抗VCA均呈阳性（P = 0.12）。该抗体的平均免疫比在病例组中为2.341，在对照组中为1.873（P = 0.068）。40例（91%）病例的IgG抗EBNA1（EB核抗原1）呈阳性，相比之下，42名对照（95%）呈阳性（P = 0.6）。
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