University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642, USA.
J Intellect Disabil Res. 2009 Nov;53(11):887-97. doi: 10.1111/j.1365-2788.2009.01199.x. Epub 2009 Sep 2.
Studies have noted high rates of specific health disorders in adults with cerebral palsy (CP). However, it remains unclear how growing older with a lifelong neuromotor physical disability confers risk for health outcomes in adults who have both intellectual disability (ID) and CP.
To assess the relationship between health status in older adults with ID either with or without coincident diagnoses of CP.
Health status data were drawn from 1373 adults aged 33 to 79 years with ID living in small group homes in New York State. Their health status was defined by the presence of common health disorders. Of these, 177 subjects had coincident CP. Prevalence data for nine diseases representing different organ systems were obtained and compared in individuals with and without CP. A Severity of Functional Impairment Index (SFII) was developed based on subjects' capabilities in activities of daily living (ADLs) and mobility. Two logistic regression analyses were conducted to determine if CP diagnosis was an independent predictor of health disorder prevalence, or rather exerted effects similar to those without CP via severity of functional impairment as determined by SFII scores. In addition, older age, gender, and severity of intellectual disability were examined as predictors of health disorder prevalence in all study subjects.
Individuals with CP had higher frequencies in four out of the nine health disorders (overweight/obesity, gastroesophageal reflux, urinary tract infections and dysphagia). Analysis revealed a statistically significant association between SFII score and CP diagnosis. CP diagnosis alone was a statistically significant predictor for all of the above four common disorders; however, after adjustment for SFII score was included in health disorder models, only dysphagia showed an independent correlation with a CP diagnosis.
With the exception of dysphagia, impairment in ADLs and walking capabilities, and not CP diagnosis alone, accounted for disparities in specific diseases. Although the diagnosis of CP may be correlated with functional impairment, it alone may play a minor role in determining health trajectories in older persons with conjoint ID and CP.
研究表明,脑瘫(CP)成年人中存在多种特定健康障碍的高发率。然而,对于那些既有智力障碍(ID)又有 CP 的成年人,随着年龄的增长,终身神经运动性残疾如何导致健康结果的风险尚不清楚。
评估同时患有 ID 和 CP 的成年人中健康状况与无 CP 成年人之间的关系。
健康状况数据来自纽约州小型集体住宅中年龄在 33 至 79 岁的 1373 名 ID 成年人。他们的健康状况由常见健康障碍的存在来定义。其中 177 名受试者患有并发 CP。获得并比较了代表不同器官系统的九种疾病的患病率数据。根据受试者在日常生活活动(ADL)和移动能力方面的能力,制定了严重功能障碍指数(SFII)。进行了两项逻辑回归分析,以确定 CP 诊断是否是健康障碍患病率的独立预测因素,或者通过 SFII 评分确定的功能障碍严重程度而产生与无 CP 相似的效果。此外,还研究了年龄较大、性别和智力障碍严重程度作为所有研究对象健康障碍患病率的预测因素。
CP 患者在九种健康障碍中的四种(超重/肥胖、胃食管反流、尿路感染和吞咽困难)的频率较高。分析显示 SFII 评分与 CP 诊断之间存在统计学显著关联。CP 诊断本身是所有上述四种常见疾病的统计学显著预测因素;然而,在健康障碍模型中纳入 SFII 评分调整后,只有吞咽困难与 CP 诊断呈独立相关性。
除了吞咽困难之外,ADL 和行走能力的损伤,而不是 CP 诊断本身,解释了特定疾病之间的差异。尽管 CP 的诊断可能与功能障碍相关,但它本身在确定具有并发 ID 和 CP 的老年人的健康轨迹方面可能只起次要作用。