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[Topical immune modulation and risk of cancer].

作者信息

Deleuran Mette, Zachariae Claus, Thestrup-Pedersen Kristian

机构信息

Dermatologisk Afdeling S, Arhus Universitetshospital, Arhus Sygehus, DK-8000 Arhus C.

出版信息

Ugeskr Laeger. 2009 Aug 24;171(35):2468-71.

PMID:19732533
Abstract

This article reviews if local immunosuppression of atopic dermatitis is associated with an increased risk of cancer - as implicated by a warning issued by the FDA and EMEA health authorities because systemic immunosuppression of transplanted patients leads to a significant increase of non-melanoma skin cancer and lymphoma. So far, no studies support that the use of topical immunosuppression increases the risk of local or systemic cancer.

摘要

相似文献

1
[Topical immune modulation and risk of cancer].
Ugeskr Laeger. 2009 Aug 24;171(35):2468-71.
2
Malignancy concerns of topical calcineurin inhibitors for atopic dermatitis: facts and controversies.特应性皮炎局部应用钙调磷酸酶抑制剂的恶性肿瘤担忧:事实与争议。
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[Calcineurin inhibitors in treatment of atopic dermatitis. Topical corticoids now only in severe outbreaks? ].[钙调神经磷酸酶抑制剂治疗特应性皮炎。局部用皮质类固醇现在仅用于严重发作期?]
MMW Fortschr Med. 2003 Jul 24;145(29-30):62.
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Report of the Topical Calcineurin Inhibitor Task Force of the American College of Allergy, Asthma and Immunology and the American Academy of Allergy, Asthma and Immunology.美国过敏、哮喘与免疫学会以及美国过敏、哮喘与免疫学院外用钙调神经磷酸酶抑制剂特别工作组报告。
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Non-melanoma skin cancer in patients with atopic dermatitis treated with topical tacrolimus.外用他克莫司治疗特应性皮炎患者的非黑色素瘤皮肤癌
J Dermatolog Treat. 2005 Aug;16(3):149-53. doi: 10.1080/09546630510041088.

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Systematic review of published trials: long-term safety of topical corticosteroids and topical calcineurin inhibitors in pediatric patients with atopic dermatitis.已发表试验的系统评价:外用糖皮质激素和外用钙调神经磷酸酶抑制剂在儿童特应性皮炎患者中的长期安全性
BMC Pediatr. 2016 Jun 7;16:75. doi: 10.1186/s12887-016-0607-9.