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主动脉瓣狭窄患者围产期麻醉管理:一项回顾性研究及文献综述

Peripartum anesthetic management of patients with aortic valve stenosis: a retrospective study and literature review.

作者信息

Ioscovich A M, Goldszmidt E, Fadeev A V, Grisaru-Granovsky S, Halpern S H

机构信息

Department of Anesthesia, Sunnybrook Health Sciences Centre, Mount Sinai Hospital, Toronto, Canada.

出版信息

Int J Obstet Anesth. 2009 Oct;18(4):379-86. doi: 10.1016/j.ijoa.2009.02.019. Epub 2009 Sep 3.

DOI:10.1016/j.ijoa.2009.02.019
PMID:19733057
Abstract

BACKGROUND

Anesthetic management of parturients with aortic stenosis is controversial. Early studies suggest maternal mortality was related to cardiac condition and anesthetic care. In this report, management of parturients with moderate or severe aortic stenosis in two institutions is compared, and published cases are reviewed.

METHODS

Peripartum anesthetic management of all parturients with moderate or severe aortic stenosis who gave birth between 1990 and 2005 at our institutions, is described. Patients with mild or non-valvular aortic stenosis were excluded.

RESULTS

There were 12 parturients, six with moderate and six with severe aortic stenosis. Two patients with moderate aortic stenosis were New York Heart Association (NYHA) classification II, the others were asymptomatic. Five patients with severe aortic stenosis were symptomatic (NYHA classification II or III). Two patients with moderate and three with severe aortic stenosis underwent cesarean delivery; epidural anesthesia was used for two. Two patients with moderate and all with serious aortic stenosis were observed postpartum for 24 to 48 h in a high-dependency unit. There were no severe maternal or neonatal complications.

CONCLUSIONS

Carefully titrated regional analgesia is usually well tolerated in patients undergoing vaginal or cesarean delivery even in the presence of severe aortic stenosis. Standard monitoring is usually adequate for vaginal delivery, but invasive monitoring may facilitate management in some patients. An arterial line allows close monitoring of systemic blood pressure. Facilities for close 24-48-h post-partum observation should be available. A multidisciplinary approach is needed.

摘要

背景

主动脉瓣狭窄产妇的麻醉管理存在争议。早期研究表明,孕产妇死亡率与心脏状况和麻醉护理有关。在本报告中,比较了两家机构中中重度主动脉瓣狭窄产妇的管理情况,并回顾了已发表的病例。

方法

描述了1990年至2005年间在我们机构分娩的所有中重度主动脉瓣狭窄产妇的围产期麻醉管理情况。排除轻度或非瓣膜性主动脉瓣狭窄患者。

结果

共有12例产妇,6例为中度主动脉瓣狭窄,6例为重度主动脉瓣狭窄。2例中度主动脉瓣狭窄患者为纽约心脏协会(NYHA)II级,其余患者无症状。5例重度主动脉瓣狭窄患者有症状(NYHA II级或III级)。2例中度和3例重度主动脉瓣狭窄患者接受了剖宫产;2例使用了硬膜外麻醉。2例中度和所有重度主动脉瓣狭窄患者产后在高依赖病房观察24至48小时。未出现严重的母婴并发症。

结论

即使存在严重主动脉瓣狭窄,仔细滴定的区域镇痛通常在接受阴道分娩或剖宫产的患者中耐受性良好。标准监测通常足以用于阴道分娩,但在某些患者中侵入性监测可能有助于管理。动脉导管可密切监测全身血压。应具备产后24至48小时密切观察的设施。需要多学科方法。

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