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Localization of the murine methylmalonyl CoA mutase (Mut) locus on chromosome 17 by in situ hybridization.

作者信息

Threadgill D W, Wilkmeyer M, Womack J E, Ledley F D

机构信息

Department of Veterinary Pathology, Texas A & M University, College Station.

出版信息

Cytogenet Cell Genet. 1990;53(2-3):112-4. doi: 10.1159/000132907.

DOI:10.1159/000132907
PMID:1973376
Abstract

Murine methylmalonyl CoA mutase (Mut) has been localized to chromosome 17C-D by in situ hybridization in cell line containing a 2.17 Robertsonian translocation. This locus, which was mapped with the help of a murine methylmalonyl CoA mutase cDNA probe, and others on murine chromosome 17 are syntenic, though not necessarily colinear, with loci on human chromosome 6.

摘要

相似文献

1
Localization of the murine methylmalonyl CoA mutase (Mut) locus on chromosome 17 by in situ hybridization.
Cytogenet Cell Genet. 1990;53(2-3):112-4. doi: 10.1159/000132907.
2
Mapping of the L-methylmalonyl-CoA mutase gene to mouse chromosome 17.
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3
Mapping of human methylmalonyl CoA mutase (MUT) locus on chromosome 6.人类甲基丙二酰辅酶A变位酶(MUT)基因座在6号染色体上的定位。
Am J Hum Genet. 1988 Jun;42(6):839-46.
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Linkage relationships of the human methylmalonyl CoA mutase to the HLA and D6S4 loci on chromosome 6.
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Assignment of the methylmalonyl-CoA mutase gene (MUT) to porcine chromosome 7q13-->q14 by in situ hybridization and analysis of radiation hybrid panels.
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Inherited methylmalonyl CoA mutase apoenzyme deficiency in human fibroblasts: evidence for allelic heterogeneity, genetic compounds, and codominant expression.人类成纤维细胞中遗传性甲基丙二酸单酰辅酶A变位酶脱辅基酶缺乏症:等位基因异质性、遗传复合性和共显性表达的证据。
J Clin Invest. 1980 Mar;65(3):690-8. doi: 10.1172/JCI109715.
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Cloning of full-length methylmalonyl-CoA mutase from a cDNA library using the polymerase chain reaction.利用聚合酶链反应从cDNA文库中克隆全长甲基丙二酰辅酶A变位酶。
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Molecular cloning of L-methylmalonyl-CoA mutase: gene transfer and analysis of mut cell lines.L-甲基丙二酰辅酶A变位酶的分子克隆:基因转移及突变细胞系分析
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Perspectives on methylmalonic acidemia resulting from molecular cloning of methylmalonyl CoA mutase.甲基丙二酰辅酶A变位酶分子克隆引发的甲基丙二酸血症研究视角
Bioessays. 1990 Jul;12(7):335-40. doi: 10.1002/bies.950120706.
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Development of transgenic mice containing an introduced stop codon on the human methylmalonyl-CoA mutase locus.开发含有人类甲基丙二酰辅酶 A 变位酶基因引入终止密码子的转基因小鼠。
PLoS One. 2012;7(9):e44974. doi: 10.1371/journal.pone.0044974. Epub 2012 Sep 14.

引用本文的文献

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Mouse models for methylmalonic aciduria.甲基丙二酸血症的小鼠模型。
PLoS One. 2012;7(7):e40609. doi: 10.1371/journal.pone.0040609. Epub 2012 Jul 9.
2
Genomic structure of murine methylmalonyl-CoA mutase: evidence for genetic and epigenetic mechanisms determining enzyme activity.小鼠甲基丙二酰辅酶A变位酶的基因组结构:决定酶活性的遗传和表观遗传机制的证据。
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Delineation of the t complex on mouse chromosome 17 by in situ hybridization.
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