Drug Ther Bull. 2009 Sep;47(9):98-101. doi: 10.1136/dtb.2009.08.0036.
One estimate suggests that at least 1 million people in the UK are on the anticoagulant warfarin.1 This number could increase as more people are treated with the drug for atrial fibrillation and as the elderly population increases.1 Careful control of anticoagulation is essential with warfarin therapy and, traditionally, patients on the drug have had to travel to a clinic to have their blood coagulation time tested. However, the availability of portable self-testing machines makes it possible for some patients to monitor their blood coagulation time at home. Here we examine the evidence on the efficacy and safety of such self-monitoring and consider which patients it most suits and whether more widespread use of the approach is justified.
一项评估表明，英国至少有100万人正在使用抗凝血药物华法林。随着越来越多的人因心房颤动接受该药物治疗以及老年人口的增加，这一数字可能会上升。对华法林治疗进行严格控制至关重要，传统上，服用该药物的患者不得不前往诊所检测凝血时间。然而，便携式自检机器的出现使得一些患者能够在家中监测自己的凝血时间。在此，我们研究了这种自我监测的有效性和安全性证据，并考虑哪些患者最适合这种方式，以及这种方法更广泛的应用是否合理。
