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一刀切是否可行?使用混合逻辑分析研究男性对良性前列腺增生治疗偏好的异质性。

Does one size fit all? Investigating heterogeneity in men's preferences for benign prostatic hyperplasia treatment using mixed logit analysis.

机构信息

Health Economics Research Unit, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen AB24 3DS, UK.

出版信息

Med Decis Making. 2009 Nov-Dec;29(6):707-15. doi: 10.1177/0272989X09341754. Epub 2009 Sep 4.

Abstract

In this study, the authors demonstrate how mixed logit analysis of discrete choice experiment (DCE) data can provide information about unobserved preference heterogeneity. Their application investigates unobserved heterogeneity in men's preferences for benign prostatic hyperplasia (BPH) treatment. They use a DCE to elicit preferences for seven characteristics of BPH treatment: time to symptom improvement, sexual and nonsexual treatment side effects, risks of acute urinary retention and surgery, cost of treatment, and reduction in prostate size. They investigate the importance of these characteristics and the trade-offs men are willing to make between them. Preferences are elicited from a sample of 100 men attending an outpatient clinic in Ireland. The authors find all treatment characteristics are significant determinants of treatment choice. There is significant preference heterogeneity in the population for four treatment characteristics: time to symptom improvement, treatment reducing prostate size, risk of surgery, and sexual side effects. The importance of preference heterogeneity at the policy level within the context of shared decision making is discussed.

摘要

在这项研究中,作者展示了如何对离散选择实验(DCE)数据进行混合逻辑分析,以提供关于未观察到的偏好异质性的信息。他们的应用研究了男性对良性前列腺增生(BPH)治疗偏好的未观察到的异质性。他们使用 DCE 来引出对 BPH 治疗的七个特征的偏好:症状改善时间、性和非性治疗副作用、急性尿潴留和手术风险、治疗成本以及前列腺大小减小。他们调查了这些特征的重要性以及男性愿意在它们之间进行的权衡。偏好是从爱尔兰一家门诊诊所的 100 名男性样本中得出的。作者发现所有治疗特征都是治疗选择的重要决定因素。在人口中,有四个治疗特征存在显著的偏好异质性:症状改善时间、治疗缩小前列腺体积、手术风险和性副作用。在共享决策的背景下,讨论了政策层面上偏好异质性的重要性。

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