Casado Mariela, Ortega Maria Gabriela, Peralta Mariana, Agnese Alicia Mariel, Cabrera Jose Luis
Farmacognosia, Departamento de Farmacia, Facultad de Ciencias Quimicas, Universidad Nacional de Cordoba, Ciudad Universitaria, Cordoba, Argentina.
Nat Prod Res. 2009;23(14):1298-303. doi: 10.1080/14786410802518201.
From the roots of Acmella decumbens (Sm) R.K. Jansen three compounds belonging to the alkamide family were isolated: (2E, 4E)-N-hydroxiphenylethyl-2,4-decadien-9-inamide (1); (4E, 6E)-N-isobutyl-4,6-undecen-10-inamide; (2) and (2Z)-N-phenylethyl-2-nonane-6,8-diinamide (3). The structures were determined by means of IR, MS, (1)H NMR, (13)C NMR, DEPT 135 and COSY. Compounds 1 and 2 are reported for the first time, while 3 was previously isolated from Spilanthes acmella L.
从平卧金纽扣（Acmella decumbens (Sm) R.K. Jansen）的根部分离出三种属于链烷酰胺家族的化合物：(2E, 4E)-N-羟基苯乙基-2,4-癸二烯-9-炔酰胺（1）；(4E, 6E)-N-异丁基-4,6-十一碳二烯-10-炔酰胺（2）；以及(2Z)-N-苯乙基-2-壬烷-6,8-二炔酰胺（3）。通过红外光谱（IR）、质谱（MS）、氢核磁共振谱（¹H NMR）、碳核磁共振谱（¹³C NMR）、DEPT 135和化学位移相关谱（COSY）确定了这些化合物的结构。化合物1和2首次被报道，而化合物3先前已从金纽扣（Spilanthes acmella L.）中分离得到。
