Jerath N U, Newman J S, Boes C J
Mayo Clinic College of Medicine, Rochester, MN, USA.
Cephalalgia. 2009 Oct;29(10):1028-33. doi: 10.1111/j.1468-2982.2009.01845.x. Epub 2009 Apr 9.
The aim of this study was to review the life of Mary E. O'Sullivan and to summarize her important contributions to the study of migraine. Mary E. O'Sullivan underwent extensive training to become a neurologist at a time when only 5% of women in America were physicians. She published five papers on migraine. In a 1936 Journal of the American Medical Association article, she described a patient with ergotamine overuse headache and recommended that daily doses of oral ergotamine should be avoided. Three years later she described migraine as a 'complex' syndrome with multiple causes and multiple cures. Mary E. O'Sullivan, an ambitious female headache specialist of the 1930s, was an early advocate of the use of ergotamine to treat migraine, yet she was one of the first to report ergotamine overuse headache. Although her life was short, her research, knowledge and ambition at a time when women had limited opportunities in medicine have left a mark.
本研究的目的是回顾玛丽·E·奥沙利文的生平,并总结她对偏头痛研究的重要贡献。玛丽·E·奥沙利文接受了广泛的培训,成为一名神经科医生,而当时美国只有5%的女性是医生。她发表了五篇关于偏头痛的论文。在1936年《美国医学会杂志》的一篇文章中,她描述了一名麦角胺过度使用性头痛患者,并建议应避免每日口服麦角胺。三年后,她将偏头痛描述为一种具有多种病因和多种治疗方法的“复杂”综合征。玛丽·E·奥沙利文是20世纪30年代一位雄心勃勃的女性头痛专家,她是使用麦角胺治疗偏头痛的早期倡导者,但她也是最早报告麦角胺过度使用性头痛的人之一。尽管她的生命短暂,但她在女性在医学领域机会有限的时代所做的研究、知识和抱负留下了印记。