Mongha Ritesh, Punit Bansal, Ranjit Das K, Anup Kundu K
Department of Urology, Institute of Post Graduate Medical Education and Research, Kolkata, India.
Saudi J Kidney Dis Transpl. 2009 Sep;20(5):838-41.
Emphysematous pyelonephritis (EPN) is an acute necrotizing parenchymal and peri-renal infection caused by gas-forming uropathogens. The predisposing factors are diabetes mellitus and ureteric obstruction. E. coli is the most frequently identified pathogen. The overall mortality is 43%. Computerized tomography (CT) is the imaging procedure of choice in determining the extent of infection and guiding management. Management of EPN has evolved from aggressive surgical intervention to conservative management. Although there are reports of improved renal function after medical therapy combined with relief of obstruction, most of the patients still require nephrectomy. We present a case of EPN and also evaluate the radiological features, prognosis, and current management of this disease.
气肿性肾盂肾炎（EPN）是一种由产气尿路病原体引起的急性坏死性实质和肾周感染。易感因素为糖尿病和输尿管梗阻。大肠杆菌是最常见的病原体。总体死亡率为43%。计算机断层扫描（CT）是确定感染范围和指导治疗的首选影像学检查方法。EPN的治疗已从积极的手术干预发展为保守治疗。虽然有报道称药物治疗联合解除梗阻后肾功能有所改善，但大多数患者仍需要进行肾切除术。我们报告一例EPN病例，并评估该疾病的影像学特征、预后及当前治疗方法。
