Billiau A
Rega Institute for Medical Research - K.U.Leuven, Minderbroedersstraat 10 - B 3000 Leuven.
Verh K Acad Geneeskd Belg. 2009;71(1-2):15-42.
In a first part of this historical article, the author overviews how, over the half century since the first in vitro demonstration of interferon, systems for large-scale production of human interferon have been elaborated and how these efforts have allowed for evaluation of the clinical potential of the different molecular types of interferon. In a second part the author reflects in more detail on research activities in Belgium aimed at production of human interferon.
在这篇历史文章的第一部分，作者概述了自首次在体外证明干扰素以来的半个世纪里，大规模生产人干扰素的系统是如何得到完善的，以及这些努力如何使人们能够评估不同分子类型干扰素的临床潜力。在第二部分中，作者更详细地回顾了比利时旨在生产人干扰素的研究活动。
