Harte James M, Pigasse Gilles, Dau Torsten
Department of Electrical Engineering, Centre for Applied Hearing Research, Technical University of Denmark, 2800 Kongens Lyngby, Denmark.
J Acoust Soc Am. 2009 Sep;126(3):1291-301. doi: 10.1121/1.3168508.
Different attempts have been made to directly measure frequency specific basilar membrane (BM) delays in animals, e.g., laser velocimetry of BM vibrations and auditory nerve fiber recordings. The present study uses otoacoustic emissions (OAEs) and auditory brainstem responses (ABRs) to estimate BM delay non-invasively in normal-hearing humans. Tone bursts at nine frequencies from 0.5 to 8 kHz served as stimuli, with care taken to quantify possible bias due to the use of tone bursts with different rise times. BM delays are estimated from the ABR latency estimates by subtracting the neural and synaptic delays. This allows a comparison between individual OAE and BM delays over a large frequency range in the same subjects, and offers support to the theory that OAEs are reflected from a tonotopic place and carried back to the cochlear base via a reverse traveling wave.
人们已经进行了不同的尝试来直接测量动物中特定频率的基底膜（BM）延迟，例如，对BM振动进行激光测速和记录听神经纤维。本研究使用耳声发射（OAE）和听觉脑干反应（ABR）来无创地估计正常听力人类的BM延迟。0.5至8kHz的九个频率的短音脉冲用作刺激，并注意量化由于使用具有不同上升时间的短音脉冲而可能产生的偏差。通过减去神经和突触延迟，从ABR潜伏期估计值中估算出BM延迟。这使得能够在同一受试者的大频率范围内比较个体的OAE和BM延迟，并为OAE从音调定位处反射并通过反向行波传回耳蜗底部的理论提供了支持。
