[武汉地区连续4年粪便潜血筛查结直肠癌项目的初步报告]

[Preliminary report about the screening program for colorectal cancer by sequential fecal occult blood in Wuhan area for 4 years].

作者信息

Lu Zhi-mei, Chen Ji-gui, Zhang Yu-xing, Wang Qian, Xu Jun, Chen Chao, Yang Rui, Xiong Fei, Liu Chang, Peng Xian-hua

机构信息

Department of Colorectal Surgery, The Eighth Hospital, Wuhan, China.

出版信息

Zhonghua Wei Chang Wai Ke Za Zhi. 2009 Sep;12(5):474-6.

PMID:19742337

Abstract

OBJECTIVE

To evaluate the sequential fecal occult blood test (SFOBT) program for the screening of colorectal cancer and elucidate the prevalence of colorectal cancer in Wuhan area.

METHODS

At 19 screening sites, 63,961 residents were recruited as target population according to random cluster and stratified sampling for four years (between 2005 and 2008). Residents aged over 40 years old received SFOBT. Those with positive SFOBT underwent colonoscopy.

RESULTS

The target population was 63,961. There were 25,837 people whose age was over 40. Finally, 7784 participants received the SFOBT screening, with a medium age of 56 years old. The positive rate of SFOBT was 12.3% (956 persons). Of the 956 persons, 240 participants underwent colonoscopy. Colorectal cancer was found in 14 cases (6.5%), gastric cancer in 2 cases (0.9%), colorectal adenoma in 53 cases(24.8%), colorectal inflammation in 80 cases (37.3%) and hemorrhoids in 65 cases (30.4%).

CONCLUSIONS

The prevalence of colorectal cancer is relatively high in Wuhan area. The SFOBT is available and feasible in screening early changes of colorectal cancer.

摘要

目的

评估序贯粪便潜血试验（SFOBT）用于结直肠癌筛查的项目，并阐明武汉地区结直肠癌的患病率。

方法

在19个筛查点，按照随机整群和分层抽样的方法，于2005年至2008年的四年间招募63961名居民作为目标人群。40岁以上居民接受SFOBT检查。SFOBT检查结果为阳性者接受结肠镜检查。

结果

目标人群为63961人。年龄在40岁以上者有25837人。最终，7784名参与者接受了SFOBT筛查，平均年龄为56岁。SFOBT阳性率为12.3%（956人）。在这956人中，240名参与者接受了结肠镜检查。发现结直肠癌14例（6.5%），胃癌2例（0.9%），结直肠腺瘤53例（24.8%），结直肠炎症80例（37.3%），痔疮65例（30.4%）。