Lopes R J, Almeida J, Dias P J, Pinho P, Maciel M J
Serviço de Cardiologia, Hospital São João, Porto, Portugal.
Clin Cardiol. 2009 Sep;32(9):488-90. doi: 10.1002/clc.20578.
Infectious thoracic aortitis (IA) remains a rare disease, especially after the appearance of antibiotics. However, if left untreated it is always lethal. It usually affects patients with atherosclerotic aortic disease and/or infective endocarditis. Mycotic aneurysm is the most common form of presentation, although a few reports of nonaneurysmal infectious thoracic aortitis have also been described. Various microorganisms have been associated with infectious thoracic aortitis, most commonly Staphylococcal, Enterococcus, Streptococcus, and Salmonella species. It is extremely important to establish an early diagnosis of IA, because this condition is potentially life-threatening. However, diagnosis is frequently delayed since clinical manifestations are usually nonspecific. Antibiotherapy in combination with complete surgical excision of the infected aorta is the best choice of treatment.
感染性胸主动脉炎(IA)仍然是一种罕见疾病,尤其是在抗生素出现之后。然而,如果不进行治疗,它总是致命的。它通常影响患有动脉粥样硬化性主动脉疾病和/或感染性心内膜炎的患者。霉菌性动脉瘤是最常见的表现形式,尽管也有一些非动脉瘤性感染性胸主动脉炎的报道。多种微生物与感染性胸主动脉炎有关,最常见的是葡萄球菌、肠球菌、链球菌和沙门氏菌属。早期诊断IA极其重要,因为这种情况可能危及生命。然而,由于临床表现通常不具特异性,诊断常常延迟。抗生素治疗联合对感染主动脉进行彻底手术切除是最佳治疗选择。