Coulon A, Milin S, Laban E, Debiais C, Jamet C, Goujon J-M
Service d'anatomie et cytologie pathologiques, unité de pathologie ultrastructurale et expérimentale, CHU La Milétrie, 2, rue de la Milétrie, BP 577, 86021 Poitiers cedex, France.
Neurochirurgie. 2009 Oct;55(4-5):454-8. doi: 10.1016/j.neuchi.2009.07.001. Epub 2009 Sep 9.
Benign tumors of the peripheral nerves come from ectodermic tissues. This chapter describes the most common forms: the schwannomas and the neurofibromas. Schwannomas have two possible patterns of cells: Antoni A and B types. Neurofibromas are most often associated with neurofibromatosis NF1 and may be localized, diffuse, or plexiform. The benign tumor structures account for the fact that they can be removed with or without preserving the concerned nerve. Malignant tumors (malignant peripheral sheath tumors) come from degeneration of neurofibromas in two out of three cases and have a poor prognosis.
周围神经的良性肿瘤起源于外胚层组织。本章描述了最常见的类型：施万细胞瘤和神经纤维瘤。施万细胞瘤有两种可能的细胞模式：Antoni A型和B型。神经纤维瘤最常与神经纤维瘤病NF1相关，可能是局限性、弥漫性或丛状的。良性肿瘤结构决定了它们在切除时可以保留或不保留相关神经。恶性肿瘤（恶性外周神经鞘瘤）在三分之二的病例中起源于神经纤维瘤的退变，预后较差。
