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Correlation of phenol sulphotransferase activities in the liver and platelets of rat.

作者信息

Nakamura J, Mizuma T, Hayashi M, Awazu S

机构信息

Department of Biopharmaceutics, Tokyo College of Pharmacy, Japan.

出版信息

J Pharm Pharmacol. 1990 Mar;42(3):207-8. doi: 10.1111/j.2042-7158.1990.tb05390.x.

Abstract

Phenol sulphotransferase (PST) activity in rat platelet cytosol for p-nitrophenol (PNP) sulphation was found to have a similar dependence on PNP concentration and thermostability to that in rat liver cytosol. The activities of PST isoenzyme for the sulphation in the microM range of PNP in rat platelets and rat liver were significantly correlated. Thus, measurement of PST activity in platelets could be a useful and practical method for predicting this activity in liver.

摘要

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