Araya Pablo, Sacks Claudio, Muñoz Paula, Gigoux Juan Pablo, García Luis, Matamala Gonzalo, Idiáquez Juan
Sección de Neurología, Servicio de Medicina Interna, Hospital Naval Almirante Nef, Viña del Mar, Chile.
Rev Med Chil. 2009 Jun;137(6):807-10. Epub 2009 Sep 4.
A primary central nervous system vasculitis is an uncommon and invalidating disease, which has a fatal course if left untreated. We report a 63 year-old woman presenting with a history of two months of cognitive impairment, dysarthria, gait instability and tremor. After four months of evolution a right hemianopsia and a flaccid paresis of upper right limb appeared. A brain biopsy was performed and the histological findings confirmed the suspicion of primary cerebral vasculitis. The patient was treated with cyclophosphamide and prednisone, observing a partial recovery of cognitive and motor function.
原发性中枢神经系统血管炎是一种罕见且使人虚弱的疾病，若不治疗会导致致命后果。我们报告一名63岁女性，有两个月认知障碍、构音障碍、步态不稳和震颤的病史。经过四个月的病情发展，出现了右侧偏盲和右上肢体弛缓性麻痹。进行了脑活检，组织学检查结果证实了原发性脑血管炎的怀疑。该患者接受了环磷酰胺和泼尼松治疗，认知和运动功能部分恢复。
