Walsh E K, Schettini A
College of Engineering, University of Florida, Gainesville 32611.
Neurol Res. 1990 Jun;12(2):123-7. doi: 10.1080/01616412.1990.11739930.
In the analysis of the pressure-volume relationship of the intracranial system, the concept of brain elastance, sometimes called tissue elastance or CSF elastance, is often used. It is generally designated as Ecsf and is calculated as the slope of the pressure-volume curve of the system. Variations in Ecsf are related to, for example, changes in the buffering capacity of the system which, however, could be influenced by the cerebral vascular volume, compressibility of the meningeal membranes, and compressibility of the subpial brain tissue. Our interest is in isolating the effect of controlled changes in the intracranial system with changes in the subpial tissue only. Here we discuss the measurement of brain tissue elasticity and describe two experimental conditions in which simultaneous measurements showed distinct differences between the behaviour of the system CSF elastance and brain tissue elastic behaviour.
在颅内系统压力-容积关系的分析中,常使用脑弹性这一概念,有时也称为组织弹性或脑脊液弹性。它通常被指定为Ecsf,并计算为系统压力-容积曲线的斜率。Ecsf的变化与例如系统缓冲能力的变化有关,然而,这可能会受到脑血管容积、脑膜的可压缩性和软脑膜下脑组织的可压缩性的影响。我们感兴趣的是仅通过软脑膜下组织的变化来分离颅内系统中受控变化的影响。在这里,我们讨论脑组织弹性的测量,并描述两种实验条件,在这两种条件下的同步测量显示,系统脑脊液弹性行为和脑组织弹性行为之间存在明显差异。