Kharkwal Shailesh, Karimi Iftekhar A, Chang Matthew Wook, Lee Dong-Yup
Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore 117576.
Recent Pat Biotechnol. 2009;3(3):202-10. doi: 10.2174/187220809789389117.
Among various renewable and sustainable energy sources being explored, biobutanol has been recognized as one of the promising alternatives for biofuels due to its attractive physical and chemical properties. Various inventions have been reported for the biological production of butanol, maintaining its competitiveness in efficiency, economy, and production scale. This article reviews such patented inventions and relevant research achievements to the microbial strains and fermentation processes for the enhanced production of biobutanol. We also discuss current challenges for strain improvement based on recent developments.
在正在探索的各种可再生和可持续能源中，生物丁醇因其具有吸引人的物理和化学性质而被认为是生物燃料有前景的替代品之一。关于生物丁醇的生物生产已有多种发明被报道，其在效率、经济性和生产规模方面保持着竞争力。本文综述了这些专利发明以及在提高生物丁醇产量的微生物菌株和发酵工艺方面的相关研究成果。我们还根据最近的进展讨论了菌株改良目前面临的挑战。
