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达托霉素对与皮肤和软组织感染相关的金黄色葡萄球菌及耐万古霉素屎肠球菌分离株的体外活性：来自印度的初步结果

In vitro activity of daptomycin against Staphylococcus aureus and vancomycin-resistant Enterococcus faecium isolates associated with skin and soft tissue infections: first results from India.

作者信息

Dhawan Benu, Gadepalli Ravisekhar, Kapil Arti

机构信息

Department of Microbiology, All India Institute of Medical Sciences, New Delhi-29, India.

出版信息

Diagn Microbiol Infect Dis. 2009 Oct;65(2):196-8. doi: 10.1016/j.diagmicrobio.2009.05.015.

DOI:10.1016/j.diagmicrobio.2009.05.015
PMID:19748433
Abstract

The in vitro activity of daptomycin and selected comparator agents against Staphylococcus aureus and vancomycin-resistant Enterococcus faecium (VREF) isolates recovered from hospitalized patients with skin and soft tissue infection's was evaluated by Clinical and Laboratory Standards Institute broth microdilution method. Daptomycin was the most active agent against both S. aureus (MIC(90), 1 microg/mL; 100% susceptible) and VREF (MIC(90), 4 microg/mL; 100% susceptible), making it an excellent therapeutic option.

摘要

采用临床和实验室标准协会肉汤微量稀释法，评估了达托霉素及选定的对照药物对从患有皮肤和软组织感染的住院患者中分离出的金黄色葡萄球菌和耐万古霉素粪肠球菌（VREF）菌株的体外活性。达托霉素是对金黄色葡萄球菌（MIC90，1微克/毫升；100%敏感）和VREF（MIC90，4微克/毫升；100%敏感）均最具活性的药物，使其成为一种出色的治疗选择。

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引用本文的文献

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