Bui L M, Bierer R L
Waltham USA, 3250 E. 44th Street, Vernon, CA 90058, USA.
Vet Ther. 2001 Spring;2(2):101-11.
This study evaluated the efficacy of green lipped mussel (GLM), added to a complete dry diet, for alleviating clinical signs of arthritis in dogs. A double-blind longitudinal study design was used with 31 mixed-breed dogs exhibiting varying degrees of arthritis. Each dog was evaluated by a veterinarian and joints were individually scored for degree of pain, swelling, crepitus, and reduction in range of movement. Summation of all scores for an individual dog comprised its total arthritis score. At baseline, dogs were randomly allocated to control and test groups. Both groups were fed the same base dry diet, to which 0.3% GLM powder was added for dogs in the test group. The change in total arthritis score by the end of 6 weeks showed there was significant improvement (P < .05) in the test group versus the control group. Significant improvements were also observed in joint pain and swelling scores in the test group. Changes in joint crepitus and range of joint movement were not significantly different between the test and control groups. These findings provide strong evidence that GLM incorporated into a complete dry diet can help alleviate arthritis symptoms in dogs.
本研究评估了添加到全价干粮中的绿唇贻贝（GLM）对缓解犬类关节炎临床症状的疗效。采用双盲纵向研究设计，对31只表现出不同程度关节炎的混种犬进行研究。每只犬由一名兽医进行评估，并对各个关节的疼痛程度、肿胀情况、摩擦音以及活动范围减小程度进行单独评分。一只犬的所有评分总和构成其总关节炎评分。在基线时，将犬随机分配到对照组和试验组。两组均饲喂相同的基础干粮，试验组的犬所喂干粮中添加了0.3%的GLM粉。6周结束时总关节炎评分的变化表明，试验组相对于对照组有显著改善（P < .05）。试验组在关节疼痛和肿胀评分方面也有显著改善。试验组和对照组在关节摩擦音和关节活动范围的变化方面无显著差异。这些发现提供了有力证据，表明添加到全价干粮中的GLM有助于缓解犬类的关节炎症状。
