Department of Radiology, Uludag University Medical Faculty, Gorukle, Bursa, Turkey.
Neuroradiology. 2010 Feb;52(2):99-108. doi: 10.1007/s00234-009-0592-x. Epub 2009 Sep 15.
In the current study, we aimed to compare the diagnostic efficacies of phase-contrast magnetic resonance imaging (PC-MRI) and three-dimensional constructive interference in steady-state (3D-CISS) sequence over detection of aqueductal stenosis (AS) on the basis of contrast-enhanced magnetic resonance cisternography (MRC).
Twenty-five patients with clinically and radiologically suspected AS were examined by PC-MRI, 3D-CISS, and MRC. Axial-sagittal PC-MRI and sagittal 3D-CISS were applied to view the cerebral aqueduct. Following injection of 0.5-1 ml intrathecal gadolinium diethylenetriamine pentaacetic acid (Gd-DTPA) injection, postcontrast MRC images were obtained in three planes in early and late phases. Aqueductal patency was scored as follows: grade 0, normal; grade 1, partial narrowing; and grade 2, complete obstruction. Results of PC-MRI and 3D-CISS were compared with the findings of MRC.
In PC-MRI, seven cases were assessed as grade 0, 16 cases grade 1, and two cases grade 2. As a result of 3D-CISS sequence, eight cases were evaluated as grade 0, 12 cases grade 1, and five cases grade 2. Based on MRC, nine cases were assessed as grade 0, whereas nine and seven cases were evaluated to be grades 1 and 2, respectively. Five cases that demonstrated partial patency in PC-MRI or 3D-CISS showed complete obstruction by MRC.
PC-MRI is helpful in confirming the AS. However, positive flow does not necessarily exclude the existence of AS. 3D-CISS sequence provides excellent cerebrospinal fluid-to-aqueduct contrast, allowing detailed study of the anatomic features of the aqueduct. MRC should be performed on patients who demonstrate suspected AS findings on PC-MRI and/or 3D-CISS sequences.
在本研究中，我们旨在比较相位对比磁共振成像（PC-MRI）和三维稳态构建干扰（3D-CISS）序列在基于对比增强磁共振脑池造影（MRC）检测 aqueductal 狭窄（AS）方面的诊断效果。
对 25 例临床和影像学疑似 AS 的患者进行 PC-MRI、3D-CISS 和 MRC 检查。采用轴位矢状 PC-MRI 和矢状 3D-CISS 观察脑 aqueduct。在鞘内注射 0.5-1ml 钆二乙烯五胺五乙酸（Gd-DTPA）后，在早晚期获得三个平面的对比后 MRC 图像。aqueductal 通畅性评分如下：0 级，正常；1 级，部分狭窄；2 级，完全阻塞。将 PC-MRI 和 3D-CISS 的结果与 MRC 的结果进行比较。
在 PC-MRI 中，7 例评分为 0 级，16 例评分为 1 级，2 例评分为 2 级。3D-CISS 序列结果为 8 例评分为 0 级，12 例评分为 1 级，5 例评分为 2 级。基于 MRC，9 例评分为 0 级，9 例和 7 例分别评分为 1 级和 2 级。在 PC-MRI 或 3D-CISS 显示部分通畅的 5 例患者，MRC 显示完全阻塞。
PC-MRI 有助于确认 AS 的存在。然而，正性流动并不能排除 AS 的存在。3D-CISS 序列提供了极好的脑脊液至 aqueduct 对比，允许详细研究 aqueduct 的解剖特征。对于在 PC-MRI 和/或 3D-CISS 序列上显示疑似 AS 表现的患者，应进行 MRC 检查。
