Trabuchet G, Dahmane M, Benabadji M
Sem Hop. 1977 Apr 23;53(16):879-81.
The existence of frequent hemoglobin abnormalities raises a Public Health problem in Algeria. The presence of genes for hemoglobin S, hemoglobin C and thalassemia in various regions of the country causes severe congenital hemolytic anemias: thalassemia, sickle-cell anemia, S thalassemia, association of HbS and HbC. These diseases are often invaliding requiring frequent admissions to hospital and have a high social cost. We have also observed certain rare hemoglobins, of which some, hemoglobin Setif, hemoglobin D Ouled Rabah were described for the first time in Algerians. They are not pathogenic in the heterozygous state.
在阿尔及利亚，频繁出现的血红蛋白异常情况引发了一个公共卫生问题。该国不同地区存在血红蛋白S、血红蛋白C和地中海贫血的基因，会导致严重的先天性溶血性贫血，如地中海贫血、镰状细胞贫血、血红蛋白S型地中海贫血、血红蛋白S与血红蛋白C的组合。这些疾病常常使人丧失劳动能力，需要频繁住院，社会成本高昂。我们还观察到了某些罕见的血红蛋白，其中一些，如塞蒂夫血红蛋白、乌尔德·拉巴赫血红蛋白，是首次在阿尔及利亚人中被描述。它们在杂合状态下不具有致病性。
