Satyanarayanan M, Chakrabarty A S, Varshney V P
Department of Physiology, Maulana Azad Medical College, New Delhi.
Indian J Med Res. 1990 Jun;92:201-4.
The effect of intracerebroventricular (icv) injection of noradrenaline (NA) on the blood pressure was studied in anaesthetised rabbits. Adrenoceptor blockers were used to study the specific adrenoceptor mediating the response. The results indicated a hypotensive response to icv injection of NA. This hypotensive response to NA was blocked by alpha-2 (yohimbine) and beta-1 (metoprolol) but not by alpha-1 (prazosin) and beta-2 (butoxamine) adrenoceptor blockers.