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外耳道恶性肿瘤的管理

Managing malignancies of the external auditory canal.

作者信息

Gidley Paul W

机构信息

University of Texas MD Anderson Cancer Center, Department of Head and Neck Surgery, 1515 Holcombe Blvd, Unit 1445, Houston, TX 77030, USA.

出版信息

Expert Rev Anticancer Ther. 2009 Sep;9(9):1277-82. doi: 10.1586/era.09.93.

Abstract

The ear canal, middle ear and temporal bone are rare sites of primary cancer. However, given its central location within the skull base, the tumors from these sites often extend to involve the parotid, overlying skin and even the dura or carotid artery. Squamous cell carcinoma is the most common histology for both primary and secondary tumors. The rarity of temporal bone cancers and the complexity of the region's anatomy make treating temporal bone malignancies difficult. While early-stage cancers can be effectively treated by complete resection, multimodal therapy is imperative for most of these tumors. A contemporary review of the literature is presented with present-day controversies outlined.

摘要

耳道、中耳和颞骨是原发性癌症的罕见部位。然而,鉴于其在颅底的中心位置,这些部位的肿瘤常常会蔓延至腮腺、覆盖的皮肤,甚至硬脑膜或颈动脉。鳞状细胞癌是原发性和继发性肿瘤最常见的组织学类型。颞骨癌的罕见性以及该区域解剖结构的复杂性使得颞骨恶性肿瘤的治疗颇具难度。虽然早期癌症可通过完整切除得到有效治疗,但对于大多数此类肿瘤而言,多模式治疗势在必行。本文对相关文献进行了当代综述,并概述了当前存在的争议。

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