Nightingale J M, Lennard-Jones J E, Walker E R, Farthing M J
St Mark's Hospital, London, UK.
Lancet. 1990 Sep 29;336(8718):765-8. doi: 10.1016/0140-6736(90)93238-k.
24 h oral intake and intestinal output were studied in 15 patients with a short residual length of jejunum and no colon. 8 patients showed a net secretory, and 7 a net absorptive response to food. In secretors, daily intestinal output exceeded oral intake (mean 2.3 kg wet weight, and 233 mmol sodium). Long-term parenteral fluid and electrolyte replacements were needed only in those with a secretory response. Jejunal length inversely correlated with net intestinal output of fluid, sodium, potassium, and with percentage energy absorption. A secretory response was observed if jejunal length was less than 100 cm and was reduced by gastric antisecretory drugs and octreotide.
对15例空肠残余长度短且无结肠的患者进行了24小时口服摄入量和肠道排出量的研究。8例患者对食物表现出净分泌反应，7例表现出净吸收反应。在分泌者中，每日肠道排出量超过口服摄入量（平均湿重2.3千克，钠233毫摩尔）。仅对有分泌反应的患者需要长期胃肠外补充液体和电解质。空肠长度与液体、钠、钾的肠道净排出量以及能量吸收百分比呈负相关。当空肠长度小于100厘米时观察到分泌反应，且胃抑分泌药物和奥曲肽可减轻该反应。
