一种用于制备注射用[（18）F]氟化钠（美国药典）的自动化方法，以应对锝-99m同位素短缺问题。
An automated method for preparation of [(18)F]sodium fluoride for injection, USP to address the technetium-99m isotope shortage.
作者信息
Hockley Brian G, Scott Peter J H
机构信息
The University of Michigan School of Medicine, Ann Arbor, MI, USA.
出版信息
Appl Radiat Isot. 2010 Jan;68(1):117-9. doi: 10.1016/j.apradiso.2009.08.012. Epub 2009 Aug 28.
Abstract
The worldwide shortage of technetium-99m has created an immediate and urgent need for access to [(18)F]sodium fluoride for PET imaging of bone metastasis. In order to facilitate global availability of [(18)F]sodium fluoride for diagnostic nuclear medicine imaging procedures, a straightforward method for rapid production of [(18)F]sodium fluoride for injection, USP, using a modified GE Tracerlab FX-FN is presented.
摘要
全球范围内锝-99m的短缺使得对用于骨转移正电子发射断层显像（PET）的[（18）F]氟化钠的获取产生了直接且迫切的需求。为了促进用于诊断性核医学成像程序的[（18）F]氟化钠在全球范围内的可得性，本文介绍了一种使用改良的通用电气Tracerlab FX-FN快速生产注射用[（18）F]氟化钠（美国药典）的简便方法。
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