Department of Neuroimmunology, Center for Brain Research, Medical University of Vienna, Spitalgasse 4, 1090, Vienna, Austria.
Semin Immunopathol. 2009 Nov;31(4):537-44. doi: 10.1007/s00281-009-0176-1. Epub 2009 Sep 11.
Epileptic seizures can be induced by a variety of underlying diseases. One of the causes is brain inflammation or encephalitis. In this review, we focus on three different kinds of encephalitis known to occur with seizures: Rasmussen encephalitis, paraneoplastic encephalitis, and nonparaneoplastic encephalitis. We describe pathogenic similarities and differences in the immunological response and cell death in the central nervous system of these three types of encephalitis and discuss the present ideas regarding the underlying etiology of these diseases.
癫痫发作可由多种基础疾病引起。其中一个原因是脑炎症或脑炎。在这篇综述中,我们重点关注三种已知可引起癫痫发作的脑炎:拉森姆脑炎、副肿瘤性脑炎和非副肿瘤性脑炎。我们描述了这三种脑炎在中枢神经系统免疫反应和细胞死亡方面的相似和不同之处,并讨论了这些疾病潜在病因的现有观点。