Feldman S, Conforti N, Saphier D
Department of Neurology, Hadassah University Hospital, Jerusalem, Israel.
Brain Res Bull. 1990 Jul;25(1):75-8. doi: 10.1016/0361-9230(90)90255-x.
The effects of a small posterior hypothalamic deafferentation (PHD) on adrenocortical responses to peripheral neural stimuli were investigated in rats. PHD inhibited the rise in plasma corticosterone (CS) following photic and acoustic stimulation, but did not affect the adrenocortical response following sciatic nerve stimulation. PHD did not change the content of norepinephrine in the paraventricular nucleus of the hypothalamus, however, it reduced the serotonin content by about 30%. The possible role of serotonin or of another tonic caudal input into the hypothalamus for the activation of the pituitary-adrenocortical axis, following certain neural stimuli, is discussed.
研究了大鼠下丘脑后部小范围去传入（PHD）对肾上腺皮质对外周神经刺激反应的影响。PHD抑制了光刺激和声刺激后血浆皮质酮（CS）的升高，但不影响坐骨神经刺激后的肾上腺皮质反应。PHD并未改变下丘脑室旁核中去甲肾上腺素的含量，然而，它使血清素含量降低了约30%。文中讨论了血清素或另一种来自下丘脑尾部的紧张性传入在某些神经刺激后激活垂体-肾上腺皮质轴方面可能发挥的作用。
