Tsai Wei-Chuan, Lee Cheng-Han, Lin Chih-Chan, Liu Yen-Wen, Huang Yao-Yi, Li Wei-Ting, Chen Ju-Yi, Lin Li-Jen
Department of Internal Medicine, National Cheng Kung University Medical Center, Tainan, Taiwan.
Echocardiography. 2009 Nov;26(10):1188-94. doi: 10.1111/j.1540-8175.2009.00954.x. Epub 2009 Sep 2.
We hypothesized that contraction of the LA wall could be documented by speckle tracking and could be applied for assessment of LA function. This study tried to identify the association between LA longitudinal strain (LAS) and strain rate (LASR) measured by speckle tracking with paroxysmal atrial fibrillation (PAF).
Fifty-two patients (61 +/- 17 years old, 23 men) with sinus rhythm at baseline referred for the evaluation of episodic palpitation were included. Standard four-chamber and two-chamber views were acquired and analyzed off-line. Peak LAS and LASR were carefully identified as the peak negative inflection of speckle tracking waves after P-wave gated by electrocardiography.
Ten patients (19%) had PAF. LAS, LASR, age, left ventricular end-diastolic dimension, left ventricular mass, LA volume, and mitral early filling-to-annulus early velocity ratio were different between patients with and without PAF. After multivariate analysis, LASR was significantly independently associated with PAF (OR 8.56, 95% CI 1.14-64.02, P = 0.036).
Speckle tracking echocardiography could be used in measurements of LAS and LASR. Decreased negative LASR was independently associated with PAF.
我们推测左心房壁的收缩可以通过斑点追踪记录下来，并可用于评估左心房功能。本研究试图确定通过斑点追踪测量的左心房纵向应变（LAS）和应变率（LASR）与阵发性心房颤动（PAF）之间的关联。
纳入52例基线时窦性心律、因发作性心悸前来评估的患者（年龄61±17岁，男性23例）。获取标准四腔心和两腔心视图并离线分析。通过心电图P波门控后，将峰值LAS和LASR仔细识别为斑点追踪波的峰值负向拐点。
10例患者（19%）患有PAF。有PAF和无PAF的患者之间，LAS、LASR、年龄、左心室舒张末期内径、左心室质量、左心房容积以及二尖瓣早期充盈与瓣环早期速度比值存在差异。多因素分析后，LASR与PAF显著独立相关（OR 8.56，95%CI 1.14 - 64.02，P = 0.036）。
斑点追踪超声心动图可用于测量LAS和LASR。LASR负值降低与PAF独立相关。
