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迟发性肺水肿和弥漫性血管内凝血与乳胶过敏反应有关。

Late-onset pulmonary edema and disseminated intravascular coagulation due to latex anaphylaxis.

机构信息

Department of Anesthesiology, Faculty of Medicine, Trakya University, 22030, Edirne, Turkey.

出版信息

Aesthetic Plast Surg. 2010 Jun;34(3):394-6. doi: 10.1007/s00266-009-9412-2. Epub 2009 Sep 19.

Abstract

BACKGROUND

Anaphylaxis after the administration of tissue expanders has been reported. Late onset hypotension, thrombocytopenia, disseminated intravascular coagulation (DIC) and pulmonary edema due to the tissue expanders have not been reported.

METHODS

In this case report, late onset hypotension, thrombocytopenia, disseminated intravascular coagulation and pulmonary edema due to the administration of tissue expanders were described.

RESULTS

The authors report a 16-year-old girl with burn scar deformities scheduled for reconstruction of the scar contractures with insertion of tissue expanders in which the administration of latex tissue expanders was associated with late onset hypotension, thrombocytopenia, disseminated intravascular coagulation and pulmonary edema. Skin tests performed for latex demonstrated strong positive weal and flare reactions.

CONCLUSION

Late onset anaphylactic reactions due to latex tissue expanders, an unusual unpredictable adverse reaction, must be kept in mind. Early recognition and proper emergent treatment are essential to reversing this complication.

摘要

背景

已有报道称在使用组织扩张器后会发生过敏反应。但尚未有迟发性低血压、血小板减少症、弥散性血管内凝血(DIC)和肺水肿与组织扩张器相关的报道。

方法

在本病例报告中,描述了一例因使用组织扩张器导致迟发性低血压、血小板减少症、弥散性血管内凝血和肺水肿的病例。

结果

作者报告了一例 16 岁女孩,患有烧伤瘢痕畸形,计划通过插入组织扩张器来重建瘢痕挛缩,在此过程中使用了乳胶组织扩张器,而乳胶组织扩张器的使用与迟发性低血压、血小板减少症、弥散性血管内凝血和肺水肿有关。对乳胶进行的皮肤测试显示出强烈的阳性风团和红斑反应。

结论

必须牢记乳胶组织扩张器引起的迟发性过敏反应,这是一种不常见且不可预测的不良反应。早期识别和适当的紧急治疗对于逆转这种并发症至关重要。

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