用于急性冠状动脉综合征早期干预的抗血小板药物：心肌挽救与出血并发症 - Suppr | 超能文献

Antiplatelet agents used for early intervention in acute coronary syndrome: myocardial salvage versus bleeding complications.

作者信息

Aranki Sary F, Body Simon C

机构信息

Division of Cardiac Surgery, Brigham and Women's Hospital, Boston, MA 02115, USA.

出版信息

J Thorac Cardiovasc Surg. 2009 Oct;138(4):807-10. doi: 10.1016/j.jtcvs.2009.04.052.

DOI:10.1016/j.jtcvs.2009.04.052

Abstract

摘要

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Antiplatelet agents used for early intervention in acute coronary syndrome: myocardial salvage versus bleeding complications.用于急性冠状动脉综合征早期干预的抗血小板药物：心肌挽救与出血并发症

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Platelet function monitoring in patients with coronary artery disease.冠状动脉疾病患者的血小板功能监测

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Pro: 'Antithrombotic therapy with warfarin, aspirin and clopidogrel is the recommended regime in anticoagulated patients who present with an acute coronary syndrome and/or undergo percutaneous coronary interventions'.专业意见：“对于出现急性冠脉综合征和/或接受经皮冠状动脉介入治疗的抗凝患者，推荐使用华法林、阿司匹林和氯吡格雷进行抗栓治疗。”

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Contra: 'Antithrombotic therapy with warfarin, aspirin and clopidogrel is the recommended regimen in anticoagulated patients who present with an acute coronary syndrome and/or undergo percutaneous coronary interventions'. Not for everybody.反对观点：“对于患有急性冠状动脉综合征和/或接受经皮冠状动脉介入治疗的抗凝患者，推荐使用华法林、阿司匹林和氯吡格雷进行抗栓治疗”。但并非适用于所有人。

Thromb Haemost. 2008 Nov;100(5):754-5.

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Improving outcomes with antiplatelet therapies in percutaneous coronary intervention and stenting.经皮冠状动脉介入治疗和支架置入术中抗血小板治疗改善预后

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Antiplatelet drug nonresponsiveness.抗血小板药物无反应性

Am Heart J. 2008 Apr;155(4):591-9. doi: 10.1016/j.ahj.2007.12.034.

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Bleeding and the use of antiplatelet agents in the management of acute coronary syndromes and atrial fibrillation.急性冠状动脉综合征和心房颤动管理中的出血及抗血小板药物的使用

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Dual antiplatelet therapy in ACS: time-dependent variability in platelet aggregation during the first week.急性冠状动脉综合征中的双联抗血小板治疗：第一周内血小板聚集的时间依赖性变异性

Indian Heart J. 2009 Mar-Apr;61(2):173-7.

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Aprotinin reduces the antiplatelet effect of clopidogrel.抑肽酶可降低氯吡格雷的抗血小板作用。

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Prasugrel: new drug. After angioplasty and stenting: continue to use aspirin + clopidogrel.普拉格雷：新药。血管成形术和支架置入术后：继续使用阿司匹林+氯吡格雷。

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