Kotsiuba A E, Babich E V, Chertok V M
Zh Nevrol Psikhiatr Im S S Korsakova. 2009;109(9):56-62.
Materials of forensic-medical autopsies of men, aged 18-44 year, who died from trauma, have been studied. Arteries of the pia mater have been taken from 26 men with arterial hypertension (AH), stages I-III, and 12 men without AH. Histochemical methods have been used to study the structure of nerve plexus of medial brain artery branches of different diameters. In AH, there were changes of the nerve plexus structure in brain arterial branches, the intensity of which was related to the vessel diameter and disease stage; the decrease of density of periadventicial adrenergic nerve plexus compared to controls, which was most intensive in AH, stage I, and in the vessels of smaller size. The changes in concentration of distinctly seen bulges (varicosities) were more significant compared to those of nervous fibers. The effectiveness of nitrooxidergic innervation was also decreased in large vessels and its structure did not visibly change in small arterial branches. In conclusion, there is a formation of vasomotor innervation dysfunction in AH.
对18 - 44岁因创伤死亡男性的法医解剖材料进行了研究。从26例患有I - III期动脉高血压（AH）的男性和12例无AH的男性身上获取软脑膜动脉。采用组织化学方法研究不同直径的大脑中动脉分支神经丛的结构。在AH患者中，脑动脉分支的神经丛结构发生改变，其强度与血管直径和疾病阶段相关；与对照组相比，外膜周围肾上腺素能神经丛密度降低，在AH I期和较小尺寸血管中最为明显。与神经纤维相比，明显可见的膨体（静脉曲张）浓度变化更为显著。大血管中硝基氧能神经支配的有效性也降低，小动脉分支中其结构无明显变化。总之，AH中存在血管运动神经支配功能障碍的形成。
