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[Open rhinophonia in adults: a rare manifestation of cranial polyneuritis].

作者信息

Heiser C, Willmann O, Bran G, Kern R, Hörmann K, Stuck B A

机构信息

Universitäts-HNO-Klinik, Universitätsmedizin Mannheim, Mannheim, Deutschland.

出版信息

HNO. 2010 Feb;58(2):155-8. doi: 10.1007/s00106-009-1913-4.

DOI:10.1007/s00106-009-1913-4
PMID:19774355
Abstract

A 46-year-old male patient reported difficulties in speech and swallowing following gastroenteritis. Marked open nasality (open rhinophonia) and swallowing difficulties with occasional passing of food into the nasopharynx was observed during speaking with the head held in an upright position. The patient was able to articulate clearly with the head reclined or in a lying position. Endoscopy identified complete bilateral soft palate paresis consistent with bilateral glossopharyngeal nerve palsy. Additional symptoms of cranial nerve palsy appeared in the course of the disease. Intravenous corticosteroids were ineffective. A marked improvement of symptoms was achieved after i.v. immunoglobulin therapy that was initiated following identification of serum IgM anti-GM 1 ganglioside antibodies under suspicion of cranial polyneuritis. Nasality was largely resolved under additional speech exercise therapy.

摘要

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Polyneuritis cranialis: full recovery after intravenous immunoglobulins.多发性颅神经炎:静脉注射免疫球蛋白后完全康复。
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Brain. 2007 Sep;130(Pt 9):2245-57. doi: 10.1093/brain/awm004. Epub 2007 Mar 2.
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Guillain-Barré syndrome.吉兰-巴雷综合征
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5
Antecedent infections in Fisher syndrome: a common pathogenesis of molecular mimicry.费希尔综合征中的前驱感染:分子模拟的常见发病机制。
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Variants and mimics of Guillain Barré Syndrome.吉兰-巴雷综合征的变异型和模仿型
Neurologist. 2004 Mar;10(2):61-74. doi: 10.1097/01.nrl.0000117821.35196.0b.
7
Peripheral neuropathies and anti-glycolipid antibodies.周围神经病变与抗糖脂抗体
Brain. 2002 Dec;125(Pt 12):2591-625. doi: 10.1093/brain/awf272.
8
Polyneuritis cranialis related to anti-GT1 a IgG antibody.与抗GT1 a IgG抗体相关的颅神经炎
J Neurol. 2001 Jan;248(1):65-6. doi: 10.1007/s004150170273.
9
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J Neurol Neurosurg Psychiatry. 1992 May;55(5):398-400. doi: 10.1136/jnnp.55.5.398.