Cummings J F, de Lahunta A
Acta Neuropathol. 1977 Jul 15;39(1):43-51. doi: 10.1007/BF00690384.
Intraneuronal accumulation of cytosomes with the fluorescent and tinctorial properties of ceroidlipofuscin occurred in the C.N.S. of a fully matured dog with signs of slowly progressive cerebellar disease. Ultrastructural study revealed various membrane-bound inclusions in addition to typical lipofuscin granules. The clinicopathologic findings in this case were contrasted with those occurring in English Setters with juvenile neuronal ceroid-lipofuscinosis, and compared with those reported in Kufs' disease in man.
在一只具有缓慢进展性小脑疾病体征的完全成熟犬的中枢神经系统中，出现了具有类蜡样脂褐质荧光和染色特性的细胞小体的神经元内积聚。超微结构研究显示，除了典型的脂褐质颗粒外，还有各种膜结合包涵体。将该病例的临床病理表现与患有幼年神经元性类蜡样脂褐质沉积症的英国塞特犬的表现进行对比，并与人类库夫斯病的报道表现进行比较。
