Smith Simon E, Roukis Thomas S
Australasian College of Podiatric Surgeons, Australia.
Clin Podiatr Med Surg. 2009 Oct;26(4):559-88. doi: 10.1016/j.cpm.2009.07.002.
Over the past two decades, autologous platelets that have been sequestered, concentrated, and mixed with thrombin to generate growth factor-concentrated platelet-rich plasma for application to bone and wounds to aide healing have been a subject of great interest. This article reviews the literature related to the use of autologous platelet-rich plasma in bone and wound healing, and reviews the processes necessary to secure a high concentration of viable platelets. Although not yet definitive, autologous platelet-rich plasma has been shown to be safe, reproducible, and effective in mimicking the natural process of bone and wound healing.
在过去二十年中,自体血小板经过隔离、浓缩,并与凝血酶混合以生成富含生长因子的血小板浓缩血浆,用于骨和伤口以促进愈合,一直是备受关注的课题。本文回顾了与自体富含血小板血浆在骨和伤口愈合中应用相关的文献,并回顾了获得高浓度活血小板所需的过程。尽管尚未定论,但自体富含血小板血浆已被证明在模拟骨和伤口愈合的自然过程中是安全、可重复且有效的。