肿瘤样脱髓鞘斑块的质子磁共振波谱和扩散加权成像

Proton magnetic resonance spectroscopy and diffusion-weighted imaging of tumefactive demyelinating plaque.

作者信息

Masu Kazuki, Beppu Takaaki, Fujiwara Shunrou, Kizawa Hideki, Kashimura Hiroshi, Kurose Akira, Ogasawara Kuniaki, Sasaki Makoto

机构信息

Department of Neurosurgery, Iwate Medical University, Morioka, Iwate.

出版信息

Neurol Med Chir (Tokyo). 2009 Sep;49(9):430-3. doi: 10.2176/nmc.49.430.

DOI:10.2176/nmc.49.430

PMID:19779292

Abstract

Proton magnetic resonance spectroscopy, diffusion-weighted axonography, and diffusion tensor tractography in a patient with tumefactive demyelination plaque (TDP) were evaluated for differential diagnosis from glioblastoma. The findings of glutamate and glutamine elevations on magnetic resonance spectroscopy and apparent tracts within the lesion on axonography and tractography were unlikely to represent glioblastoma, and were thus useful for the preoperative diagnosis of TDP.

摘要

对一名患有肿胀性脱髓鞘斑块（TDP）的患者进行了质子磁共振波谱、扩散加权轴突造影和扩散张量纤维束成像，以与胶质母细胞瘤进行鉴别诊断。磁共振波谱上谷氨酸和谷氨酰胺升高以及轴突造影和纤维束成像上病变内的明显纤维束的表现不太可能代表胶质母细胞瘤，因此对TDP的术前诊断有用。