Du Hui-Ai, Zhang Xing-Guo, Tang Ri-Yuan, Li Jin-Heng
College of Chemistry and Materials Science, Wenzhou University, Wenzhou 325035, China.
J Org Chem. 2009 Oct 16;74(20):7844-8. doi: 10.1021/jo9016309.
An efficient synthesis of 3-chalcogen-benzo[b]furans via palladium-promoted annulation reactions of 2-alkynylphenol derivatives with disulfides or diselenides and iodide has been developed. In the presence of I(2) and PdCl(2), both 3-sulfenylbenzofurans and 3-selenenylbenzofurans were selectively prepared from the cyclization of 2-alkynyanisoles with disulfides or diselenides in moderate to excellent yields.
通过钯促进的2-炔基苯酚衍生物与二硫化物或二硒化物及碘化物的环化反应，已开发出一种高效合成3-硫属元素苯并[b]呋喃的方法。在碘和二氯化钯存在下，由2-炔基苯甲醚与二硫化物或二硒化物环化反应可选择性地制备3-亚磺酰基苯并呋喃和3-亚硒酰基苯并呋喃，产率中等至优异。
