Limaiem Faten, Bellil Selma, Bellil Khadija, Chelly Inès, Mekni Amina, Khaldi Moncef, Haouet Slim, Zitouna Moncef, Kchir Nidhameddine
Department of Pathology, La Rabta Hospital, Bab Saâdoun, 1007 Tunis, Tunisia.
Clin Neurol Neurosurg. 2010 Jan;112(1):23-8. doi: 10.1016/j.clineuro.2009.09.001. Epub 2009 Sep 24.
To analyze epidemiological characteristics, clinical symptoms, radiological aspects, treatment and outcome of central nervous system hydatidosis and compare our results with those reported in literature.
In our retrospective study, we reviewed 39 cases of primary central nervous system hydatid cysts operated on in our hospital between 1998 and 2007.
There were 20 male and 19 female patients (sex-ratio M/F=1.05) between 2 and 68 years of age (mean=26.5 years). Thirteen of the patients were children (33.3%) with a mean age of 6.8 years and 26 were adults (66.7%) with a mean age of 36.3 years. The location of hydatid cysts was intracranial in 27 cases (69.2%) and spinal in 12 cases (30.8%). Headache and motor deficits were the predominant symptoms in patients with intracranial hydatidosis whereas back pain and spinal cord compression syndrome were the most frequent clinical presentations in patients with spinal hydatidosis. All patients underwent surgical resection of the cyst. Pathologic findings were consistent with hydatid cyst in all cases. During the follow-up period which ranged between 12 months and 5 years, 12 patients had recurrence (30.7%). Only one patient with intracranial hydatid cyst died postoperatively due to anaphylactic shock.
Despite all the advances in imaging techniques and therapeutic methods, central nervous system hydatidosis remains difficult to cure and patient outcomes are not satisfactory especially in case of spinal involvement due to the high incidence of recurrence.
分析中枢神经系统包虫病的流行病学特征、临床症状、影像学表现、治疗方法及预后，并将我们的结果与文献报道的结果进行比较。
在我们的回顾性研究中，我们回顾了1998年至2007年间在我院接受手术治疗的39例原发性中枢神经系统包虫囊肿病例。
患者年龄在2至68岁之间（平均26.5岁），其中男性20例，女性19例（性别比M/F = 1.05）。13例患者为儿童（33.3%），平均年龄6.8岁，26例为成人（66.7%），平均年龄36.3岁。包虫囊肿位于颅内27例（69.2%），位于脊髓12例（30.8%）。头痛和运动功能障碍是颅内包虫病患者的主要症状，而背痛和脊髓压迫综合征是脊髓包虫病患者最常见的临床表现。所有患者均接受了囊肿手术切除。所有病例的病理结果均与包虫囊肿相符。在12个月至5年的随访期内，12例患者复发（30.7%）。仅1例颅内包虫囊肿患者术后因过敏性休克死亡。
尽管在影像技术和治疗方法方面取得了所有进展，但中枢神经系统包虫病仍然难以治愈，尤其是在脊髓受累的情况下，由于复发率高，患者的预后并不理想。
