Toronto Lung Transplant Program, Division of Thoracic Surgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.
J Heart Lung Transplant. 2009 Oct;28(10):1116-8. doi: 10.1016/j.healun.2009.06.022.
A 19-year-old man with cystic fibrosis, who was on extracorporeal membrane oxygenation, underwent bilateral lung transplantation from a donor with glioblastoma multiforme. Because the risk of tumor transmission from donor-related central nervous system malignancies remains unclear, the use of these extended donors remains controversial. In fact, there are few reports on the outcomes of lung transplantation from donors with central nervous system malignancy. This patient was critically ill with extracorporeal membrane oxygenation support before transplantation, but is well without any sign of malignancy 20 months after transplantation.
一名 19 岁的囊性纤维化患者正在接受体外膜氧合治疗,他接受了一名患有胶质母细胞瘤的供体的双侧肺移植。由于供体相关中枢神经系统恶性肿瘤传播的风险尚不清楚,因此这些扩展供体的使用仍然存在争议。事实上,关于中枢神经系统恶性肿瘤供体的肺移植结果的报告很少。该患者在移植前因体外膜氧合支持而病重,但在移植后 20 个月,他身体状况良好,没有任何恶性肿瘤的迹象。