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胸主动脉瘤的治疗指征。

Indications for the treatment of thoracic aortic aneurysms.

作者信息

Elefteriades John A, Botta Donald M

机构信息

Section of Cardiac Surgery, Yale University School of Medicine, 330 Cedar Street, Boardman 204, New Haven, CT 06510, USA.

出版信息

Surg Clin North Am. 2009 Aug;89(4):845-67, ix. doi: 10.1016/j.suc.2009.06.005.

DOI:10.1016/j.suc.2009.06.005
PMID:19782841
Abstract

In an era of increasingly common and detailed imaging of the thorax, thoracic aortic aneurysms are being discovered in their precomplicated state with increasing frequency. At the same time, the list of potential treatments for thoracic aneurysms is beginning to expand. Deciding which treatment method to employ and which aneurysm to treat is often difficult. The risk of aneurysm complications must be balanced against the risks of the treatment. This work explores the behavior of thoracic aneurysms, the state-of-the-art in treatment, and a rational approach to the treatment decision is proposed.

摘要

在胸部成像日益普遍且详细的时代,胸主动脉瘤在其未出现复杂病变的状态下被发现的频率越来越高。与此同时,胸主动脉瘤的潜在治疗方法列表也开始不断扩充。决定采用哪种治疗方法以及治疗哪个动脉瘤往往颇具难度。动脉瘤并发症的风险必须与治疗风险相权衡。本文探讨了胸主动脉瘤的特性、当前的治疗技术水平,并提出了一种合理的治疗决策方法。

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Syndecan-1 Is Overexpressed in Human Thoracic Aneurysm but Is Dispensable for the Disease Progression in a Mouse Model.Syndecan-1在人类胸主动脉瘤中过度表达,但在小鼠模型中对疾病进展并非必需。
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