马拉维感染 HIV 的女性产后恢复性生活和月经规律。

Resumption of sexual activity and regular menses after childbirth among women infected with HIV in Malawi.

机构信息

Department of Obstetrics and Gynecology and Medicine, University of Malawi, Blantyre, Malawi.

出版信息

Int J Gynaecol Obstet. 2010 Jan;108(1):26-30. doi: 10.1016/j.ijgo.2009.08.014.

DOI:10.1016/j.ijgo.2009.08.014

PMID:19782980

Abstract

OBJECTIVE

To determine the factors associated with resumption of sexual activity and regular menses after childbirth among women infected with HIV-1.

METHODS

Information on sociodemographic, behavioral, and clinical factors was obtained from 2 HIV perinatal studies (NVAZ and PEPI trials) conducted in Malawi, 2000-2009. Factors associated with resumption of sexual activity and menses were analyzed using Cox proportional hazard models.

RESULTS

A total of 1838 women from the NVAZ study and 2982 women from the PEPI study were included in the analysis. Resumption of sexual activity was primarily associated with sociodemographic factors (e.g. in the PEPI study, marital status [adjusted hazard ratio (aHR) 0.56, P<0.001], use of contraceptive method [aHR 8.0, P<0.001], and breastfeeding [aHR 0.52, P<0.001]), whereas resumption of regular menses in the PEPI study was primarily associated with biological factors (e.g. plasma viral load [aHR 0.89, P<0.006], and breastfeeding [aHR 0.23, P<0.001).

CONCLUSION

HIV-infected women need adequate counseling to take into account their HIV infection status before resuming sexual activity after childbirth.

摘要

目的

确定与 HIV-1 感染妇女产后恢复性生活和正常月经相关的因素。

方法

我们从 2000 年至 2009 年在马拉维开展的两项 HIV 围产期研究（NVAZ 和 PEPI 试验）中获取了社会人口学、行为和临床因素方面的信息。采用 Cox 比例风险模型分析与恢复性生活和月经相关的因素。

结果

共有 1838 名来自 NVAZ 研究的妇女和 2982 名来自 PEPI 研究的妇女纳入了分析。性生活的恢复主要与社会人口学因素相关（例如，在 PEPI 研究中，婚姻状况[调整后的风险比（aHR）为 0.56，P<0.001]、使用避孕方法[aHR 为 8.0，P<0.001]和母乳喂养[aHR 为 0.52，P<0.001]），而在 PEPI 研究中月经恢复正常主要与生物学因素相关（例如，血浆病毒载量[aHR 为 0.89，P<0.006]和母乳喂养[aHR 为 0.23，P<0.001]）。