Najjar Marwan W, Azzam Narmer I, Baghdadi Tarafa S, Turkmani Ali H, Skaf Ghassan
Department of Surgery, Neurosurgery Division, American University of Beirut Medical Center, Beirut, Lebanon.
Clin Neurol Neurosurg. 2010 Jan;112(1):17-22. doi: 10.1016/j.clineuro.2009.08.027. Epub 2009 Sep 23.
The study is aimed at evaluating neuroendoscopic procedures in the management of various intra-cranial intra-ventricular lesions.
We retrospectively review 24 consecutive patients harboring various intra-ventricular lesions with or without associated hydrocephalus, operated and managed by the authors between December 2002 and December 2007. Depending on the preoperative imaging and working diagnosis, endoscopic biopsy or endoscopic resection/debulking, along with concomitant treatment of hydrocephalus via third ventriculostomy or fenestration of the septum pellucidum and ventriculo-peritoneal shunting, were done.
The single endoscopic procedure was successful in most of the patients (22/24), where the goals of surgery in attaining a diagnostic biopsy or resection, and simultaneous treatment of hydrocephalus, were attained helping guide further therapy. The endoscopic procedure was the only procedure needed in most of the patients.
The endoscopic procedures carried a high success rate in the management of intra-ventricular lesions, and were especially valuable in patients harboring chemo and/or radiosensitive deep seated tumors.
本研究旨在评估神经内镜手术在治疗各种颅内脑室病变中的应用。
我们回顾性分析了2002年12月至2007年12月期间由作者手术治疗的24例连续患者,这些患者患有各种脑室病变,伴有或不伴有脑积水。根据术前影像学检查和初步诊断,进行了内镜活检或内镜切除/减瘤手术,并通过第三脑室造瘘术或透明隔造瘘术以及脑室-腹腔分流术同步治疗脑积水。
大多数患者(22/24)单次内镜手术成功,达到了手术获取诊断性活检或切除以及同步治疗脑积水的目标,有助于指导进一步治疗。内镜手术是大多数患者唯一需要的手术。
内镜手术在治疗脑室病变方面成功率高,对患有化疗和/或放疗敏感的深部肿瘤患者尤其有价值。